Immunology & Hematology

Mechanisms of the Immune Response

Unit 7 Introduction

The units previously covered have discussed antigen, antibody, cells and tissues involved in the immune response and the MHC and HLA antigens. This unit discusses how these elements interact to mount an immune response in an individual exposed to a foreign antigen. The areas of immune tolerance and immunomodulation are described as well as the action of immunosuppressive agents and when immunosuppression is beneficial.

 

Objectives
Upon completion of this unit, the student will be able to:
 
1.
 Describe the following in relation to the immune response:
  1. Presentation of antigen through antibody production
  2. Primary response
  3. Secondary response
  4. Switch in IgM antibody production to IgG by B lymphocytes
  5. Production of polyclonal antibodies and their advantages
2.
 Explain the mechanism involved in T-independent immune response.
3.

Describe cell mediated immunity.
4.
 Discuss the following in relation to immunity:
  1. Immune tolerance
  2. Immunomodulation
5.

Discuss the following in relation to immunosuppression:

  1. Immunosuppressive agents
  2. Conditions in which immunosuppression is beneficial
  3. Adverse effects
 

Activities
 
 

7.1 Immune Response

 
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